Carbenoxolone disodium
Cat. No.：YN300061
CAS No. ：7421-40-1
| 产品名称: | Carbenoxolone disodium |
| CAS No.: | 7421-40-1 |
| Chemical Name: | (3β,20β)-3-(3-carboxy-1-oxopropoxy)-11-oxo-olean-12-en-29-oic acid, disodium salt |
| Synonyms: | Bioral,甘珀酸钠,Duogastrone,Biogastrone |
| 分子量: | 614.72 |
| 分子式: | C₃₄H₄₈Na₂O₇ |
| SMILES: | CC(C)([C@]1([H])CC[C@@]([C@@]2(CC[C@]3(CC[C@](C[C@@]3([H])C2=C4)(C)C(O[Na])=O)C)C)5C)[C@@H](OC(CCC(O[Na])=O)=O)CC[C@]1(C)[C@@]5([H])C4=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Carbenoxolone disodium 是甘草酸 (HY-N0184) 的活性代谢物和人11β-HSD和细菌3α, 20β-HSD的抑制剂。Carbenoxolone disodium 是一种缝隙连接的解耦剂 (gap junctions) 和并且可以有效抑制牛痘病毒生长。Carbenoxolone disodium 可用于研究消化性、食道和口腔溃疡和炎症的相关研究。 |
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Sircus, W.Carbenoxolone sodiumGut13(10),816-824(1972)
Quinkler, M., and Stewart, P.M.Hypertension and the cortisol-cortisone shuttleJ. Clin. Endocrinol. Metab.88(6),2384-2392(2003)
Hellmich, H.L., Rojo, D.R., Micci, M.A., et al.Pathway analysis reveals common pro-survival mechanisms of metyrapone and carbenoxolone after traumatic brain injuryPLoS One8(1),e53230(2013)
