Gap 26
Cat. No.：YN300074
| 产品名称: | Gap 26 |
| CAS No.: | 197250-15-0 |
| Chemical Name: | L-valyl-L-cysteinyl-L-tyrosyl-L-α-aspartyl-L-lysyl-L-seryl-L-phenylalanyl-L-prolyl-L-isoleucyl-L-seryl-L-histidyl-L-valyl-L-arginine, trifluoroacetate salt |
| Synonyms: | |
| 分子量: | 1550.78 |
| 分子式: | C₇₀H₁₀₆N₁₉O₁₉S |
| SMILES: | CC[C@H](C)[C@@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CN=CN1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)O)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CC3=CC=CC=C3)NC(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC4=CC=C(C=C4)O)NC(=O)[C@H](CS)NC(=O)[C@H |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Gap 26 是一种连接蛋白 (connexin) 模拟肽，由连接蛋白 connexin 43 (gap junction 阻滞剂)第一个胞外环的第 63-75 残基组成，包含SHVR氨基酸基序。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Chaytor, A.T., Evans, W.H., and Griffith, T.M.Peptides homologous to extracellular loop motifs of connexin 43 reversibly abolish rhythmic contractile activity in rabbit arteriesJ. Physiol.503(1),99-110(1997)
Braet, K., Vandamme, W., Martin, P.E.M., et al.Photoliberating inositol-1,4,5-trisphosphate triggers ATP release that is blocked by the connexin mimetic peptide gap 26Cell Calcium33(1),37-48(2003)
Hawat, G., Hélie, P., and Baroudi, G.Single intravenous low-dose injections of connexin 43 mimetic peptides protect ischemic heart in vivo against myocardial infarctionJ. Mol. Cell. Cardiol.53(4),559-566(2012)
