Glabrescione B
Cat. No.:YN450052
产品名称: | Glabrescione B |
CAS No.: | 65893-94-9 |
Chemical Name: | |
Synonyms: | GlaB |
分子量: | 450.52 |
分子式: | C₂₇H₃₀O₆ |
SMILES: | O=C1C(C2=CC=C(OC/C=C(C)/C)C(OC/C=C(C)/C)=C2)=COC3=CC(OC)=CC(OC)=C13 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Glabrescione B 是第一个结合 Hedgehog (Hh) 调节剂Gli1并通过干扰Gli1-DNA相互作用而削弱其活性的化合物。Glabrescione B 抑制 Hedgehog 依赖性肿瘤细胞的生长,抑制肿瘤源性干细胞的自我更新能力和克隆能力。 |
IC50和靶点: | |
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In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |