GANT 58
Cat. No.：YN450075
CAS No. ：64048-12-0
规格
价格(RMB)
库存
| 产品名称: | GANT 58 |
| CAS No.: | 64048-12-0 |
| Chemical Name: | 4,4’,4’’,4’’’-(2,3,4,5-thiophenetetrayl)tetrakis-pyridine |
| Synonyms: | NSC 75503 |
| 分子量: | 392.48 |
| 分子式: | C₂₄H₁₆N₄S |
| SMILES: | C1(C2=C(C(C3=CC=NC=C3)=C(S2)C4=CC=NC=C4)C5=CC=NC=C5)=CC=NC=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | GANT 58 是一种有效的Gli拮抗剂，抑制 GLI1 诱导的转录，IC50为 5 μM。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Stanton, B.Z., and Peng, L.F.Small-molecule modulators of the Sonic Hedgehog signaling pathwayMol. Biosyst.6(1),44-54(2010)
Joo, J., Christensen, L., Warner, K., et al.GLI1 is a central mediator of EWS/FLI1 signaling in Ewing tumorsPLoS One4(10),(2009)
Beauchamp, E., Bulut, G., Abaan, O., et al.GLI1 is a direct transcriptional target of EWS-FLI1 oncoproteinJ. Biol. Chem.284(14),9074-9082(2009)
