GANT 61
Cat. No.:YN450085
产品名称: | GANT 61 |
CAS No.: | 500579-04-4 |
Chemical Name: | 2,2'-[[dihydro-2-(4-pyridinyl)-1,3(2H,4H)-pyrimidinediyl]bis(methylene)]bis(N,N-dimethyl-benzenamine) |
Synonyms: | NSC 136476 |
分子量: | 429.60 |
分子式: | C₂₇H₃₅N₅ |
SMILES: | CN(C)C1=CC=CC=C1CN2C(C3=CC=NC=C3)N(CC4=CC=CC=C4N(C)C)CCC2 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | GANT 61 是靶向Hedgehog/GLi通路的Gli1和Gli2抑制剂。 |
IC50和靶点: | |
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Lauth, M., Bergström, Å., Shimokawa, T., et al.Inhibition of GLI-mediated transcription and tumor cell growth by small-molecule antagonistsProc. Natl. Acad. Sci. USA104(20),8455-8460(2007)