AZD7594
Cat. No.:YN320437
CAS No. :1196509-60-0
产品名称: | AZD7594 |
CAS No.: | 1196509-60-0 |
Chemical Name: | 3-[5-[(1R,2S)-2-[(2,2-Difluoro-1-oxopropyl)amino]-1-(2,3-dihydro-1,4-benzodioxin-6-yl)propoxy]-1H-indazol-1-yl]-N-[(3R)-tetrahydro-3-furanyl]benzamide; AZD 7594; AZD-7594; AZD7594; |
Synonyms: | AZ13189620 |
分子量: | 606.62 |
分子式: | C₃₂H₃₂F₂N₄O₆ |
SMILES: | O=C(N[C@H]1COCC1)C2=CC=CC(N3N=CC4=C3C=CC(O[C@H](C5=CC=C(OCCO6)C6=C5)[C@@H](NC(C(F)(F)C)=O)C)=C4)=C2 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | AZD7594 是一种有效的,选择性非甾体类糖皮质激素受体 (glucocorticoid receptor) 调节剂,IC50值为 0.9 nM。 |
IC50和靶点: | |
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McMillan A. E., et al.: J. Organic Chem., 84, 4629 (2019)
Hemmerling, M., et al.: J. Med. Chem., 60, 8591 (2017)