Exicorilant
Cat. No.:YN320512
CAS No. :1781244-77-6
产品名称: | Exicorilant |
CAS No.: | 1781244-77-6 |
Chemical Name: | |
Synonyms: | CORT 125281 |
分子量: | 589.56 |
分子式: | C₂₆H₂₃F₄N₇O₃S |
SMILES: | O=C([C@]12CC3=C(N(C4=CC=C(F)C=C4)N=C3)C[C@]1([H])CCN(S(=O)(C5=NN(C)N=C5)=O)C2)C6=NC=CC(C(F)(F)F)=C6 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Exicorilant (CORT 125281) 是选择性的、并具有口服活性的糖皮质激素受体 (GR)的拮抗剂,其Ki值为 7 nM。Exicorilant (CORT 125281) 具有克服肥胖、葡萄糖不耐受和血脂异常的潜能。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |