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Betamethasone

Cat. No.:YN320755

  • CAS No. :378-44-9

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    • 参考文献
    • 产品名称: Betamethasone
      CAS No.: 378-44-9
      Chemical Name: 9-fluoro-11β,17,21-trihydroxy-16β-methyl-pregna-1,4-diene-3,20-dione
      Synonyms:倍他米松
      分子量:392.46
      分子式:C₂₂H₂₉FO₅
      SMILES:C[C@@]12[C@](C[C@H](C)[C@]2(O)C(CO)=O)([H])[C@]3([H])CCC4=CC(C=C[C@]4(C)[C@@]3(F)[C@@H](O)C1)=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: Betamethasone 是一种合成糖皮质激素,具有抗炎和免疫抑制活性。Betamethasone 可加速胎儿肺成熟并诱导基因表达和细胞凋亡。
      IC50和靶点:
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      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Corbel, M., Lagente, V., Théret, N., et al.Comparative effects of betamethasone, cyclosporin and nedocromil sodium in acute pulmonary inflammation and metalloproteinase activities in bronchoalveolar lavage fluid from mice exposed to lipopolysaccharidePulm. Pharmacol. Ther.12(3),165-171(1999)

      van der Merwe, J., van der Veeken, L., Inversetti, A., et al.Neurocognitive sequelae of antenatal corticosteroids in a late preterm rabbit modelAm. J. Obstet. Gynecol.226(6),850.e851-850.e821(2022)

      Galaz, J., Romero, R., Arenas-Hernandez, M., et al.Betamethasone as a potential treatment for preterm birth associated with sterile intra-amniotic inflammation: A murine studyJ. Perinat. Med.49(7),897-906(2021)

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