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Deflazacort

Cat. No.:YN320764

  • CAS No. :14484-47-0

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    • 生物活性
    • 参考文献
    • 产品名称: Deflazacort
      CAS No.: 14484-47-0
      Chemical Name: 21-(acetyloxy)-11β-hydroxy-2'-methyl-5'H-pregna-1,4-dieno[17,16β-d]oxazole-3,20-dione
      Synonyms:地夫可特
      分子量:441.52
      分子式:C₂₅H₃₁NO₆
      SMILES:O=C1C=C[C@@]2(C)C(CC[C@]3([H])[C@]2([H])[C@@H](O)C[C@@]4(C)[C@@]3([H])C[C@]5([H])[C@@]4(C(COC(C)=O)=O)N=C(C)O5)=C1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: Deflazacort 是一种糖皮质激素,一种无活性的前药,可迅速转化为活性代谢物 21-Desacetyldeflazacort。Deflazacort 可作为抗炎和免疫抑制剂。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Canonica, G.W., Ciprandi, G., Passalacqua, G., et al.Molecular events in allergic inflammation: Experimental models and possible modulationAllergy52(suppl 34),25-30(1997)

      Czaja, A.J.Promising pharmacological, molecular and cellular treatments of autoimmune hepatitisCurr. Pharm. Des.17(29),3120-3140(2011)

      Matthews, E., Brassington, R., Kuntzer, T., et al.Corticosteroids for the treatment of Duchenne muscular dystrophyCochrane Database Syst. Rev.5,CD003725(2016)

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