Cortisone
Cat. No.：YN321142
| 产品名称: | Cortisone |
| CAS No.: | 53-06-5 |
| Chemical Name: | 17,21-dihydroxy-pregn-4-ene-3,11,20-trione |
| Synonyms: | 可的松; 17-Hydroxy-11-dehydrocorticosterone; Kendall's compound E |
| 分子量: | 360.44 |
| 分子式: | C₂₁H₂₈O₅ |
| SMILES: | C[C@@]1(C2)[C@](C(CO)=O)(O)CC[C@@]1([H])[C@]3([H])CCC4=CC(CC[C@]4(C)[C@@]3([H])C2=O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Cortisone (17-Hydroxy-11-dehydrocorticosterone)，是 Cortisol（一种糖皮质激素）的氧化代谢产物。Cortisone 具有免疫抑制和消炎的作用。Cortisone 在高浓度下可以部分干预 Glucocorticoid 与Glucocorticoid-receptor的结合。 |
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Dammann, C., Stapelfeld, C., and Maser, E.Expression and activity of the cortisol-activating enzyme 11β-hydroxysteroid dehydrogenase type 1 is tissue and species-specificChem. Biol. Interact.303,57-61(2019)
Viglietti, A.I.P., Giambartolomei, G.H., and Delpino, M.V.Endocrine modulation of Brucella abortus-infected osteocytes function and osteoclastogenesis via modulation of RANKL/OPGMicrobes Infect.21(7),287-295(2019)
