Methylprednisolone
Cat. No.：YN321438
| 产品名称: | Methylprednisolone |
| CAS No.: | 83-43-2 |
| Chemical Name: | 11β,17,21-trihydroxy-6α-methyl-pregna-1,4-diene-3,20-dione |
| Synonyms: | 甲泼尼龙; U 7532 |
| 分子量: | 374.47 |
| 分子式: | C₂₂H₃₀O₅ |
| SMILES: | O=C1C=C[C@]2(C)[C@@]3([H])[C@@H](O)C[C@]4(C)[C@@](O)(C(CO)=O)CC[C@@]4([H])[C@]3([H])C[C@H](C)C2=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Methylprednisolone 是皮质类固醇，可作用于糖皮质激素受体。Methylprednisolone 通过激活ACE2并降低 IL-6 水平来改善严重的COVID-19。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Brownie, A.C.The metabolism of adrenal cortical steroidsThe Adrenal Gland2,209-225(1992)
Coghlan, M.J., Kym, P.R., Elmore, S.W., et al.Synthesis and characterization of non-steroidal ligands for the glucocorticoid receptor: Selective quinoline derivatives with prednisolone-equivalent functional activityJ. Med. Chem.44,2879-2885(2001)
