Triamcinolone
Cat. No.:YN321454
产品名称: | Triamcinolone |
CAS No.: | 124-94-7 |
Chemical Name: | (11β,16α)-9-fluoro-11,16,17,21-tetrahydroxy-pregna-1,4-diene-3,20-dione |
Synonyms: | 曲安奈德 |
分子量: | 394.43 |
分子式: | C₂₁H₂₇FO₆ |
SMILES: | F[C@@]1([C@]2(C=C3)C)[C@](CCC2=CC3=O)([H])[C@@](C[C@@H](O)[C@]4(O)C(CO)=O)([H])[C@]4(C)C[C@@H]1O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Triamcinolone 是合成的长效糖皮质激素,是皮质类固醇激素受体 (corticosteroid hormone receptor) 激动剂,具有抗炎作用。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Hayashi, R., Xiao, W., Kawamoto, M., et al.Systemic glucocorticoid therapy reduces pain and the number of endoneurial tumor necrosis factor-alpha (TNFα)-positive mast cells in rats with a painful peripheral neuropathyJ. Pharmacol. Sci.106(4),599-565(2008)
Uete, T., and Ashmore, J.Effects of triamcinolone on carbohydrate synthesis by rat liver slicesJ. Biol. Chem.238(9),2906-2911(1963)
Wada, S., Udagawa, N., Akatsu, T., et al.Regulation by calcitonin and glucocorticoids of calcitonin receptor gene expression in mouse osteoclastsEndocrinology138(2),521-529(1997)
Shetlar, M.R., Shetlar, D.J., Bloom, R.F., et al.Involution of keloid implants in athymic mice treated with pirfenidone or with triamcinoloneJ. Lab Clin. Med.132(6),491-496(1998)