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Fluocinolone (Acetonide)

Cat. No.:YN321488

  • CAS No. :67-73-2

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Fluocinolone (Acetonide)
      CAS No.: 67-73-2
      Chemical Name: 6α,9-difluoro-11β,21-dihydroxy-16α,17-[(1-methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dione
      Synonyms:醋酸肤轻松
      分子量:452.49
      分子式:C₂₄H₃₀F₂O₆
      SMILES:O=C([C@]([C@@]1([H])C[C@@]2([H])[C@@](C[C@H](F)C3=CC4=O)([H])[C@@](F)([C@]3(C=C4)C)[C@@H](O)C5)(OC(C)(C)O1)[C@]25C)CO
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Fluocinolone Acetonide是糖皮质激素衍生物,可作用于各种皮肤病。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Nehmé, A., Lobenhofer, E.K., Stamer, W.D., et al.Glucocorticoids with different chemical structures but similar glucocorticoid receptor potency regulate subsets of common and unique genes in human trabecular meshwork cellsBMC Med. Genomics.2,58(2009)

      Ayalasomayajula, S.P., Ashton, P., and Kompella, U.B.Fluocinolone inhibits VEGF expression via glucocorticoid receptor in human retinal pigment epithelial (ARPE-19) cells and TNF-α-induced angiogenesis in chick chorioallantoic membrane (CAMJ. Ocul. Pharmacol. Ther.25(2),97-103(2009)

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