Medroxyprogesterone acetate
Cat. No.：YN321511
| 产品名称: | Medroxyprogesterone acetate |
| CAS No.: | 71-58-9 |
| Chemical Name: | 17-(acetyloxy)-6α-methyl-pregn-4-ene-3,20-dione |
| Synonyms: | 醋酸甲羟孕酮; Medroxyprogesterone 17-acetate; MPA |
| 分子量: | 386.52 |
| 分子式: | C₂₄H₃₄O₄ |
| SMILES: | CC(O[C@@]([C@]12C)(CC[C@@]1([H])[C@@](C[C@H](C)C3=CC4=O)([H])[C@]([C@]3(CC4)C)([H])CC2)C(C)=O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Medroxyprogesterone acetate 是一种广泛使用的合成类固醇，与孕酮 (progesterone)，雄激素 (androgen) 和糖皮质激素受体 (glucocorticoid receptors) 都有作用。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Chang, M.C.Effects of medroxyprogesterone acetate and of ethinyl oestradiol on the fertilization and transportation of ferret eggsJ. Reprod. Fertil.13(1),173-174(1967)
Dickmann, Z.Short- and long-term effects of a single injection of depo-medroxyprogesterone acetate (provera) on the vaginal smear, ovulation and mating in the ratJ. Reprod. Fertil.32(3),447-451(1973)
Albin, J., Vittek, J., Gordon, G.G., et al.On the mechanism of the anti-androgenic effect of medroxyprogesterone acetateEndocrinology93(2),(1973)
Huijbregts, R.P., Michel, K.G., and Hel, Z.Effect of progestins on immunity: Medroxyprogesterone but not norethisterone or levonorgestrel suppresses the function of T cells and pDCsContraception90(2),123-129(2014)
Turcotte, J.G., Haines, R.F., Brody, G.L., et al.Immunosuppression with medroxyprogesterone acetateTransplantation6(2),248-260(1968)
Hofmeyr, G.J., Singata-Madliki, M., Lawrie, T.A., et al.Effects of the copper intrauterine device versus injectable progestin contraception on pregnancy rates and method discontinuation among women attending termination of pregnancy services in South Africa: A pragmatic randomized controlled trialReprod. Health13,42(2016)
