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Fluocinonide

Cat. No.:YN321516

  • CAS No. :356-12-7

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Fluocinonide
      CAS No.: 356-12-7
      Chemical Name: 21-(acetyloxy)-6α,9-difluoro-11β-hydroxy-16α,17-[(1-methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dione
      Synonyms:氟轻松
      分子量:494.52
      分子式:C₂₆H₃₂F₂O₇
      SMILES:O=C([C@]([C@@]1([H])C[C@@]2([H])[C@@](C[C@H](F)C3=CC4=O)([H])[C@@](F)([C@]3(C=C4)C)[C@@H](O)C5)(OC(C)(C)O1)[C@]25C)COC(C)=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Fluocinonide (Vanos)是糖皮质激素类固醇,具有抗炎活性,可作用于皮肤疾病。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Avery, A.M., and Chittiboyina, A.G.Anti‐inflammatory glucocorticoidsBurger's medicinal chemistry, drug discovery and development7,35-152(2010)

      Viaje, A., Slaga, T.J., Wigler, M., et al.Effects of antiinflammatory agents on mouse skin tumor promotion, epidermal DNA synthesis, phorbol ester-induced cellular proliferation, and production of plasminogen activatorCancer Res.37(5),1530-1536(1977)

      Wang, J., Barak, L.S., Mook, R.A., Jr., et al.Glucocorticoid hedgehog agonists in neurogenesisStem Cell Regulators87,207-215(2011)

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