Betamethasone valerate
Cat. No.：YN321566
| 产品名称: | Betamethasone valerate |
| CAS No.: | 2152-44-5 |
| Chemical Name: | 9-fluoro-11β,21-dihydroxy-16β-methyl-17-[(1-oxopentyl)oxy]-pregna-1,4-diene-3,20-dione |
| Synonyms: | Betamethasone 17-valerate |
| 分子量: | 476.58 |
| 分子式: | C₂₇H₃₇FO₆ |
| SMILES: | C[C@@]12[C@](C(CO)=O)(OC(CCCC)=O)[C@@H](C)C[C@@]1([H])[C@]3([H])CCC4=CC(C=C[C@]4(C)[C@@]3(F)[C@@H](O)C2)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Betamethasone valerate (Betamethasone 17-valerate) 是 Betamethasone 的 17 戊酸酯，是一种具有抗炎活性的局部皮质类固醇，有抗炎活性。Betamethasone valerate 可用于复发性口疮的研究。Betamethasone valerate 抑制放射标记的糖皮质激素地塞米松 (3H dexamethasone) 与人表皮和小鼠皮肤的结合，IC50分别为 5 和 6 nM。 |
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Epstein, E.H., Jr., and Bonifas, J.M.Glucocorticoid receptors of normal human epidermisJ. Invest. Dermatol.78(2),144-146(1982)
Iizuka, Y., Endo, Y., and Misawa, Y.Two simple methods for the evaluation of topically active anti-inflammatory steroidal ointmentsAgents Actions11(3),254-259(1981)
