Dexamethasone phosphate disodium
Cat. No.：YN321683
| 产品名称: | Dexamethasone phosphate disodium |
| CAS No.: | 2392-39-4 |
| Chemical Name: | (11β,16α)-9-fluoro-11,17-dihydroxy-16-methyl-21-(phosphonooxy)-pregna-1,4-diene-3,20-dione, disodium salt |
| Synonyms: | 地塞米松磷酸二钠; Dexamethasone 21-phosphate disodium salt |
| 分子量: | 516.40 |
| 分子式: | C₂₂H₂₈FNa₂O₈P |
| SMILES: | O=C1C=C[C@@]2(C)C(CC[C@]3([H])[C@]2(F)[C@@H](O)C[C@@]4(C)[C@@]3([H])C[C@@H](C)[C@]4(O)C(COP(O[Na])(O[Na])=O)=O)=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Dexamethasone phosphate disodium is aglucocorticoid receptoragonist. |
| IC50和靶点: | |
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Hui, B., Yao, X., Zhang, L., et al.Dexamethasone sodium phosphate attenuates lipopolysaccharide-induced neuroinflammation in microglia BV2 cellsNaunyn Schmiedebergs Arch. Pharmacol.393(9),1761-1768(2020)
Katz, R.J., and Carroll, B.J.Endocrine control of psychomotor activity in the rat: Effects of chronic dexamethasone upon general activityPhysiol. Behav.20(1),25-30(1978)
Rauchhaus, U., Schwaiger, F.W., and Panzner, S.Separating therapeutic efficacy from glucocorticoid side-effects in rodent arthritis using novel, liposomal delivery of dexamethasone phosphate: Long-term suppression of arthritis facilitates interval treatmentArthritis Res. Ther.11(6),R190(2009)
McClintock, D., Austel, M., Gogal, R.M., Jr., et al.Oral dexamethasone sodium phosphate solution significantly reduces pruritus and clinical lesions in feline hypersensitivity dermatitis: An open-label studyVet. Dermatol.32(5),497-e137(2021)
