Fluorometholone
Cat. No.：YN321685
| 产品名称: | Fluorometholone |
| CAS No.: | 426-13-1 |
| Chemical Name: | 9-fluoro-11β,17-dihydroxy-6α-methyl-pregna-1,4-diene-3,20-dione |
| Synonyms: | 氟米龙 |
| 分子量: | 376.46 |
| 分子式: | C₂₂H₂₉FO₄ |
| SMILES: | CC([C@@]1(O)CC[C@@]2([H])[C@]3([H])C[C@H](C)C4=CC(C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)=O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Fluorometholone 是一种合成糖皮质激素，能作为糖皮质激素受体 (glucocorticoid receptor) 激动剂，具有抗炎和抗过敏特性。Fluorometholone 可用于干眼症的研究。 |
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Southren, A.L., Dominquez, M.O., Gordon, G.G., et al.Nuclear translocation of the cytoplasmic glucocorticoid receptor in the iris-ciliary body and adjacent corneoscleral tissue of the rabbit following topical administration of various glucocorticoids. A rapid screening method for glucocorticoid activityInvest. Ophthalmol. Vis. Sci.24(2),147-152(1983)
Lin, M.T.Demonstration of specific glucocorticoid binding sites in bovine corneaExp. Eye Res.38,333-339(1984)
Lee, L.S., Kim, Y.H., and Park, Y.M.The toxicity of nonsteroidal anti-inflammatory eye drops against human corneal epithelial cells in vitroJ. Korean Med. Sci.30(12),1856-1864(2015)
