Methylprednisolone succinate
Cat. No.：YN321687
CAS No. ：2921-57-5
| 产品名称: | Methylprednisolone succinate |
| CAS No.: | 2921-57-5 |
| Chemical Name: | 21-(3-carboxy-1-oxopropoxy)-11β,17-dihydroxy-6α-methyl-pregna-1,4-diene-3,20-dione |
| Synonyms: | 甲基泼尼松龙琥珀酸酯; Methylprednisolone hydrogen succinate |
| 分子量: | 474.54 |
| 分子式: | C₂₆H₃₄O₈ |
| SMILES: | C[C@@]12[C@](C(COC(CCC(O)=O)=O)=O)(O)CC[C@@]1([H])[C@]3([H])C[C@H](C)C4=CC(C=C[C@]4(C)[C@@]3([H])[C@@H](O)C2)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Methylprednisolone succinate 是一种合成的糖皮质激素，被广泛用作抗炎剂。 |
| IC50和靶点: | |
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Vree, T.B., Lagerwerf, A.J., Verwey-van Wissen, C.P., et al.High-performance liquid chromatography analysis, preliminary pharmacokinetics, metabolism and renal excretion of methylprednisolone with its C6 and C20 hydroxy metabolites in multiple sclerosis patients receiving high-dose pulse therapyJ. Chromatogr. B Biomed. Sci. Appl.732(2),337-348(1999)
Hori, T., Jin, L., Fujii, A., et al.Dexamethasone-mediated transcriptional regulation of rat carboxylesterase 2 geneXenobiotica42(7),614-623(2012)
Avnir, Y., Ulmansky, R., Wasserman, V., et al.Amphipathic weak acid glucocorticoid prodrugs remote-loaded into sterically stabilized nanoliposomes evaluated in arthritic rats and in a Beagle dog: A novel approach to treating autoimmune arthritisArthritis Rheum.58(1),119-129(2008)
