(20S)-Protopanaxatriol
Cat. No.:YN321735
CAS No. :34080-08-5
产品名称: | (20S)-Protopanaxatriol |
CAS No.: | 34080-08-5 |
Chemical Name: | (3β,6α,12β)-dammar-24-ene-3,6,12,20-tetrol |
Synonyms: | 20 (S)-原人参三醇; 20(S)-APPT; g-PPT |
分子量: | 476.73 |
分子式: | C₃₀H₅₂O₄ |
SMILES: | C[C@]([C@@](C[C@H]1O)([H])[C@]2(CC[C@@H]3O)C)(C[C@H](O)[C@@]2([H])C3(C)C)[C@]4([C@@]1([H])[C@]([C@@](C)(O)CC/C=C(C)/C)([H])CC4)C |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | (20S)-Protopanaxatriol 是人参皂苷的代谢物,通过glucocorticoid receptor和oestrogen receptor起作用,同时为LXRα的抑制剂。 |
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Helms, S.Cancer prevention and therapeutics: Panax ginsengAltern. Med. Rev.9(3),259-274(2004)
Tian, Y., Guo, H., Han, J., et al.Microbial transformation of 20(S)-protopanaxatriol by Mucor spinosusJ. Nat. Prod.68(5),678-680(2005)
Usami, Y., Liu, Y.-N., Lin, A.-S., et al.Antitumor agents. 261. 20(S)-Protopanaxadiol and 20(s)-protopanaxatriol as antiangiogenic agents and total assignment of 1H NMR spectraJ. Nat. Prod.71(3),478-481(2008)
Oh, G.S., Pae, H.O., Choi, B.M., et al.20(S)-Protopanaxatriol, one of ginsenoside metabolites, inhibits inducible nitric oxide synthase and cyclooxygenase-2 expressions through inactivation of nuclear factor-κB in RAW 264.7 macrophages stimulated with lipopolysaccharideCancer Lett.205(1),23-29(2004)