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(20S)-Protopanaxatriol

Cat. No.:YN321735

  • CAS No. :34080-08-5

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    • 参考文献
    • 产品名称: (20S)-Protopanaxatriol
      CAS No.: 34080-08-5
      Chemical Name: (3β,6α,12β)-dammar-24-ene-3,6,12,20-tetrol
      Synonyms:20 (S)-原人参三醇; 20(S)-APPT; g-PPT
      分子量:476.73
      分子式:C₃₀H₅₂O₄
      SMILES:C[C@]([C@@](C[C@H]1O)([H])[C@]2(CC[C@@H]3O)C)(C[C@H](O)[C@@]2([H])C3(C)C)[C@]4([C@@]1([H])[C@]([C@@](C)(O)CC/C=C(C)/C)([H])CC4)C
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: (20S)-Protopanaxatriol 是人参皂苷的代谢物,通过glucocorticoid receptor和oestrogen receptor起作用,同时为LXRα的抑制剂。
      IC50和靶点:
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      Solvent & Solubility:
    • Helms, S.Cancer prevention and therapeutics: Panax ginsengAltern. Med. Rev.9(3),259-274(2004)

      Tian, Y., Guo, H., Han, J., et al.Microbial transformation of 20(S)-protopanaxatriol by Mucor spinosusJ. Nat. Prod.68(5),678-680(2005)

      Usami, Y., Liu, Y.-N., Lin, A.-S., et al.Antitumor agents. 261. 20(S)-Protopanaxadiol and 20(s)-protopanaxatriol as antiangiogenic agents and total assignment of 1H NMR spectraJ. Nat. Prod.71(3),478-481(2008)

      Oh, G.S., Pae, H.O., Choi, B.M., et al.20(S)-Protopanaxatriol, one of ginsenoside metabolites, inhibits inducible nitric oxide synthase and cyclooxygenase-2 expressions through inactivation of nuclear factor-κB in RAW 264.7 macrophages stimulated with lipopolysaccharideCancer Lett.205(1),23-29(2004)

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