ODQ
Cat. No.:YN320119
CAS No. :41443-28-1
产品名称: | ODQ |
CAS No.: | 41443-28-1 |
Chemical Name: | 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one |
Synonyms: | 1H-ODQ |
分子量: | 187.15 |
分子式: | C₉H₅N₃O₂ |
SMILES: | O=C1ON=C2N1C3=C(C=CC=C3)N=C2 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | ODQ 是一种有效的选择性可溶性鸟苷酰环化酶(sGC)抑制剂。ODQ 增强顺铂促人间皮瘤细胞凋亡的作用。 |
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Garthwaite, J., Southam, E., Boulton, C.L., et al.Potent and selective inhibition of nitric oxide-sensitive guanylyl cyclase by 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-oneMol. Pharmacol.48(2),184-188(1995)
Schrammel, A., Behrends, S., Schmidt, K., et al.Characterization of 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one as a heme-site inhibitor of nitric oxide-sensitive guanylyl cyclaseMol. Pharmacol.50(1),1-5(1996)