Praliciguat
Cat. No.:YN320397
CAS No. :1628730-49-3
产品名称: | Praliciguat |
CAS No.: | 1628730-49-3 |
Chemical Name: | |
Synonyms: | IW-1973 |
分子量: | 534.36 |
分子式: | C₂₁H₁₄F₈N₆O₂ |
SMILES: | FC1=C(C=CC=C1)CN2C(C3=NOC=C3)=CC(C4=NC=C(F)C(NCC(C(F)(F)F)(O)C(F)(F)F)=N4)=N2 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Praliciguat (IW-1973) 是一种有效、可口服的可溶性鸟甘酸环化酶 (soluble guanylate cyclase) 促进剂,增强 NO 信号通路,为血管舒张剂。在 HEK-293 细胞中,Praliciguat (IW-1973) 能够刺激 sGC,EC50值为 197 nM。 |
IC50和靶点: | |
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Clinical Trial: | |
Solvent & Solubility: |