BAY 41-2272
Cat. No.：YN320581
CAS No. ：256376-24-6
| 产品名称: | BAY 41-2272 |
| CAS No.: | 256376-24-6 |
| Chemical Name: | 5-cyclopropyl-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-4-pyrimidinamine |
| Synonyms: | BAY 41-2272, 256376-24-6, UNII-34A162J6WB, IN1523, BAY-41-2272, 3-(4-Amino-5-cyclopropylpyrimidin-2-yl)-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine |
| 分子量: | 360.39 |
| 分子式: | C₂₀H₁₇FN₆ |
| SMILES: | NC1=NC(C2=NN(CC3=CC=CC=C3F)C4=NC=CC=C42)=NC=C1C5CC5 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | BAY 41-2272是一种可溶性鸟苷酸环化酶 (sGC) 活化剂。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
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Stasch, J.P., Becker, E.M., Alonso-Alija, C., et al.NO-independent regulatory site on soluble guanylate cyclaseNature410,212-215(2001)
Evgenov, O.V., Pacher, P., Schmidt, P.M., et al.NO-independent stimulators and activators of soluble guanylate cyclase: Discovery and therapeutic potentialNat. Rev. Drug Discov.5(9),755-768(2006)
Stasch, J.P., Alonso-Alija, C., Apeler, H., et al.Pharmacological actions of a novel NO-independent guanylyl cyclase stimulator, BAY 41-8543: In vitro studiesBr. J. Pharmacol.135,333-343(2002)
