Riociguat
Cat. No.：YN320910
CAS No. ：625115-55-1
| 产品名称: | Riociguat |
| CAS No.: | 625115-55-1 |
| Chemical Name: | N-[4,6-diamino-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-pyrimidinyl]-N-methyl-carbamic acid, methyl ester |
| Synonyms: | 利奥西呱; BAY 632521 |
| 分子量: | 422.42 |
| 分子式: | C₂₀H₁₉FN₈O₂ |
| SMILES: | FC1=CC=CC=C1CN2C3=NC=CC=C3C(C4=NC(N)=C(C(N)=N4)N(C)C(OC)=O)=N2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Riociguat (BAY 632521) 是一种可口服的可溶性鸟苷酸环化酶 (sGC) 刺激剂，常用于研究肺动脉高压症。 |
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Schermuly, R.T., Stasch, J.P., Pullamsetti, S.S., et al.Expression and function of soluble guanylate cyclase in pulmonary arterial hypertensionEur. Respir. J.32(4),881-891(2008)
Stasch, J.P., Pacher, P., and Evgenov, O.V.Soluble guanylate cyclase as an emerging therapeutic target in cardiopulmonary diseaseCirculation123(20),2263-2273(2011)
