Lificiguat
Cat. No.：YN320933
CAS No. ：170632-47-0
| 产品名称: | Lificiguat |
| CAS No.: | 170632-47-0 |
| Chemical Name: | 5-[1-(phenylmethyl)-1H-indazol-3-yl]-2-furanmethanol |
| Synonyms: | YC-1 |
| 分子量: | 304.34 |
| 分子式: | C₁₉H₁₆N₂O₂ |
| SMILES: | OCC1=CC=C(C2=NN(CC3=CC=CC=C3)C4=C2C=CC=C4)O1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Lificiguat 结合到可溶性鸟苷酸环化酶(sGC)的β亚基，在CO存在条件下，Kd为 0.6-1.1 μM。 |
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Wu, C.C., Ko, F.N., Kuo, S.C., et al.YC-1 inhibited human platelet aggregation through NO-independent activation of soluble guanylate cyclaseBr. J. Pharmacol.116(3),1973-1978(1995)
Ko, F.N., Wu, C.C., Kuo, S.C., et al.YC-1, a novel activator of platelet guanylate cyclaseBlood84(12),4226-4233(1994)
Friebe, A., Schultz, G., and Koesling, D.Sensitizing soluble guanylyl cyclase to become a highly CO-sensitive enzymeEMBO J.15(24),6863-6868(1996)
