Taribavirin hydrochloride
Cat. No.:YN250115
CAS No. :40372-00-7
产品名称: | Taribavirin hydrochloride |
CAS No.: | 40372-00-7 |
Chemical Name: | 1-β-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboximidamide Monohydrochloride; |
Synonyms: | AVS-206, AVS 206, AVS206, ICN-3142, ICN 3142, ICN3142, KD-024, KD 024, KD024, Taribavirin hydrochloride, Ribamidine, Viramidine, Taribavirin HCl |
分子量: | 279.68 |
分子式: | C₈H₁₄ClN₅O₄ |
SMILES: | N=C(C1=NN([C@H]2[C@@H]([C@@H]([C@@H](CO)O2)O)O)C=N1)N.Cl |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Taribavirin hydrochloride 是一种具有口服活性的肌苷-磷酸脱氢酶抑制剂,具有抗多种病毒的活性,特别是丙型肝炎病毒和流感病毒。Taribavirin hydrochloride 是利巴韦林前药,旨在集中在肝脏内以靶向 HCV 感染的肝细胞,同时最小化红细胞 (RBC) 内的分布和溶血性贫血的发展。 |
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Lin, C., et al.: Antivir. Chem. Chemother., 14, 145 (2003), Wu, J.Z., et al.: Antimicrob. Agents Chemother., 48, 4006 (2004), Aora, S., et al.: J. Clin. Pharmacol., 45, 275 (2005),