JNJ-632
Cat. No.:YN250218
CAS No. :1572510-42-9
产品名称: | JNJ-632 |
CAS No.: | 1572510-42-9 |
Chemical Name: | N-(4-fluoro-3-methylphenyl)-3-[[[(3S)-tetrahydro-3-furanyl]amino]sulfonyl]-benzamide |
Synonyms: | JNJ-632 |
分子量: | 378.42 |
分子式: | C₁₈H₁₉FN₂O₄S |
SMILES: | O=C(NC1=CC=C(F)C(C)=C1)C2=CC=CC(S(=O)(N[C@@H]3COCC3)=O)=C2 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | JNJ-632 是一种乙型肝炎病毒 (HBV) 衣壳组装调节剂 (CAM)。 |
IC50和靶点: | |
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Vandyck, K., Rombouts, G., Stoops, B., et al.Synthesis and evaluation of N-phenyl-3-sulfamoyl-benzamide derivatives as capsid assembly modulators inhibiting hepatitis B virus (HBV)J. Med. Chem.61(14),6247-6260(2018)
Berke, J.M., Dehertogh, P., Vergauwen, K., et al.Capsid assembly modulators have a dual mechanism of action in primary human hepatocytes infected with hepatitis B virusAntimicrob. Agents Chemother.61(8),pii: e00560-00176(2017)