Bicyclol
Cat. No.:YN251128
CAS No. :118159-48-1
产品名称: | Bicyclol |
CAS No.: | 118159-48-1 |
Chemical Name: | 5'-(hydroxymethyl)-7,7'-dimethoxy-[4,4'-bi-1,3-benzodioxole]-5-carboxylic acid, methyl ester |
Synonyms: | 双环醇; SY801 |
分子量: | 390.34 |
分子式: | C₁₉H₁₈O₉ |
SMILES: | O=C(C1=CC(OC)=C(OCO2)C2=C1C3=C4OCOC4=C(OC)C=C3CO)OC |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Bicyclol(SY 801)是可口服的抗HBV,HCV化合物。 |
IC50和靶点: | |
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Liu, G.T.Bicyclol: A novel drug for treating chronic viral hepatitis B and CMed. Chem.5(1),29-43(2009)
Li, M., and Liu, G.T.Inhibition of Fas/FasL mRNA expression and TNF-a release in concanavalin A-induced liver injury in mice by bicyclolWorld J. Gastroenterol.10(12),1775-1790(2004)
Yu, L., Wei, H., and Liu, G.A novel antihepatitis drug, bicyclol, prevents liver carcinogenesis in diethylnitrosamine-initiated and phenobarbital-promoted mice tumor modelJ. Biomed. Biotechnol.,(2012)
Zhen, Y.Z., Li, N.R., He, H.W., et al.Protective effect of bicyclol against bile duct ligation-induced hepatic fibrosis in ratsWorld J. Gastroenterol.21(23),7155-7164(2015)