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Isoscopoletin

Cat. No.:YN251551

  • CAS No. :776-86-3

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Isoscopoletin
      CAS No.: 776-86-3
      Chemical Name: 6-hydroxy-7-methoxy-2H-1-benzopyran-2-one
      Synonyms:6-Hydroxy-7-methoxycoumarin
      分子量:192.17
      分子式:C₁₀H₈O₄
      SMILES:O=C1C=CC2=CC(O)=C(OC)C=C2O1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: Isoscopoletin (6-Hydroxy-7-methoxycoumarin) 是艾叶中的一种活性成分。 Isoscopoletin 具有显著的细胞增殖抑制作用,对人类 CCRF-CEM 白血病细胞和耐药亚系 CEM/ADR5000 作用的 IC50值分别为 4.0 μM 和 1.6 μM。Isoscopoletin (6-Hydroxy-7-methoxycoumarin) 具有抑制 HBV 复制的活性。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Zhao, D.-D., Zhao, Q.-S., Liu, L., et al.Compounds from Dryopteris fragrans (L.) Schott with cytotoxic activityMolecules19(3),3345-3355(2014)

      Nazir, S., Li, B., Tahir, K., et al.Antimicrobial activity of five constituents isolated from Ranunculus muricatusJ. Med. Plants Res.7(47),3438-3443(2013)

      Deng, S., Palu, A.K., West, B.J., et al.Lipoxygenase inhibitory constituents of the fruits of noni (Morinda citrifolia) collected in TahitiJ. Nat. Prod.70(5),859-862(2007)

      Selim, Y.A., and Ouf, N.H.Anti-inflammatory new coumarin from the Ammi majus LOrg. Med. Chem. Lett.2(1),1(2012)

      Meyer, R.P., Hagemeyer, C.E., Knoth, R., et al.Oxidative hydrolysis of scoparone by cytochrome P450 CYP2C29 reveals a novel metaboliteBiochem. Biophys. Res. Commun.285(1),32-39(2001)

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