(S)-Tenofovir
Cat. No.:YN251957
CAS No. :147127-19-3
产品名称: | (S)-Tenofovir |
CAS No.: | 147127-19-3 |
Chemical Name: | P-[[(1S)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]-phosphonic Acid; (S)-9-(2-Phosphonomethoxypropyl)adenine; (S)-PMPA; |
Synonyms: | (S)-替诺福韦; (S)-GS 1278; (S)-PMPA; (S)-TDF |
分子量: | 287.21 |
分子式: | C₉H₁₄N₅O₄P |
SMILES: | OP(O)(CO[C@@H](C)CN1C=NC2=C(N)N=CN=C12)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | (S)-Tenofovir ((S)-GS 1278) 是 Tenofovir 的低活性 S 型异构体。Tenofovir 是一种核苷酸逆转录酶 (nucleotide reverse transcriptase) 抑制剂,可用于 HIV 和慢性乙型肝炎的研究 (Hepatitis B; HBV)。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Balzarini, J. et al: Biochem. Biophys. Res. Comm., 219, 337 (1996)
Balzarini, J. et al.: Antimicrob. Agents. Ch., 37, 332 (1993)
Thormar, H. et al.: Antimicorb. Agents. Ch., 37, 2540 (1993)