BLT-1
Cat. No.：YN250258
| 产品名称: | BLT-1 |
| CAS No.: | 321673-30-7 |
| Chemical Name: | 2-(2-hexylcyclopentylidene)-hydrazinecarbothioamide |
| Synonyms: | BLT1;BLT-1;BLT 1 |
| 分子量: | 241.40 |
| 分子式: | C₁₂H₂₃N₃S |
| SMILES: | CCCCCCC1CCC/C1=N/NC(N)=S |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | BLT-1 是一种硫半碳杂铜螯合剂，选择性清道夫受体 B1 型 (SR-BI) 抑制剂。BLT-1 抑制 SR-BI 介导的脂质在高密度脂蛋白 (HDL) 和细胞之间的转移。BLT-1 是一种有效的 HCV 进入抑制剂。BLT-1 通过中性粒细胞募集而具有促炎功能。 |
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Nieland, T.J.F., Penman, M., Dori, L., et al.Discovery of chemical inhibitors of the selective transfer of lipids mediated by the HDL receptor SR-BIProc. Natl. Acad. Sci. USA99(24),15422-15427(2002)
Raldúa, D., and Babin, P.J.BLT-1, a specific inhibitor of the HDL receptor SR-BI, induces a copper-dependent phenotype during zebrafish developmentToxicol. Lett.175(1-3),1-7(2007)
