Velpatasvir
Cat. No.：YN250363
CAS No. ：1377049-84-7
| 产品名称: | Velpatasvir |
| CAS No.: | 1377049-84-7 |
| Chemical Name: | N-[(1R)-2-[(2S,4S)-2-[5-[1,11-dihydro-2-[(2S,5S)-1-[(2S)-2-[(methoxycarbonyl)amino]-3-methyl-1-oxobutyl]-5-methyl-2-pyrrolidinyl][2]benzopyrano[4',3':6,7]naphth[1,2-d]imidazol-9-yl]-1H-imidazol-2-yl]-4-(methoxymethyl)-1-pyrrolidinyl]-2-oxo-1-phenylethyl]- |
| Synonyms: | 维帕他韦; GS-5816 |
| 分子量: | 883.00 |
| 分子式: | C₄₉H₅₄N₈O₈ |
| SMILES: | O=C(N([C@H]1C)[C@@H](CC1)C2=NC3=C(C(C=C(OCC4=CC(C5=CN=C([C@H](C[C@H](COC)C6)N6C([C@@H](C7=CC=CC=C7)NC(OC)=O)=O)N5)=CC=C84)C8=C9)=C9C=C3)N2)[C@H](C(C)C)NC(OC)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Velpatasvir (VEL, GS-5816是一个新颖的NS5A抑制剂。 |
| IC50和靶点: | |
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| Clinical Trial: | |
| Solvent & Solubility: |
Lawitz, E., Freilich, B., Link, B., et al.A phase 1, randomized, dose-ranging study of GS-5816, a once-daily NS5A inhibitor, in patients with genotype 1-4 hepatitis C virusJ. Viral. Hepat.22(12),1011-1019(2015)
Nguyenla, X., Wehri, E., Van Dis, E., et al.Discovery of SARS-CoV-2 antiviral synergy between remdesivir and approved drugs in human lung cellsSci. Rep.12(1),18506(2022)
