Dasabuvir
Cat. No.：YN250579
CAS No. ：1132935-63-7
| 产品名称: | Dasabuvir |
| CAS No.: | 1132935-63-7 |
| Chemical Name: | N-[6-[5-(3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-3-(1,1-dimethylethyl)-2-methoxyphenyl]-2-naphthalenyl]-methanesulfonamide |
| Synonyms: | ABT-333 |
| 分子量: | 493.57 |
| 分子式: | C₂₆H₂₇N₃O₅S |
| SMILES: | CS(=O)(NC1=CC=C2C=C(C3=CC(N(C(N4)=O)C=CC4=O)=CC(C(C)(C)C)=C3OC)C=CC2=C1)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Dasabuvir (ABT-333) 是一种非核苷抑制剂，抑制RNA依赖性的HCV NS5B基因编码的 RNA 聚合酶，抑制 HCV 基因型 1a 和 1b 临床分离株衍生的重组 NS5B 聚合酶，IC50为 2.2 到 10.7 nM。 |
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| Solvent & Solubility: |
Kati, W., Koev, G., Irvin, M., et al.In vitro activity and resistance profile of dasabuvir, a nonnucleoside hepatitis C virus polymerase inhibitorAntimicrob. Agents Chemother.59(3),1505-1511(2015)
