Deferiprone
Cat. No.：YN251100
| 产品名称: | Deferiprone |
| CAS No.: | 30652-11-0 |
| Chemical Name: | 3-hydroxy-1,2-dimethyl-4(1H)-pyridinone |
| Synonyms: | 去铁酮 |
| 分子量: | 139.15 |
| 分子式: | C₇H₉NO₂ |
| SMILES: | O=C1C(O)=C(C)N(C)C=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Deferiprone 是唯一口服有活性的铁螯合剂, 用于研究地中海贫血中的输血性铁过载。 |
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Barnabé, N., Zastre, J.A., Venkataram, S., et al.Deferiprone protects against doxorubicin-induced myocyte cytotoxicityFree Radic. Biol. Med.33(2),266-275(2002)
Zheng, J., Sato, M., Mishima, E., et al.Sorafenib fails to trigger ferroptosis across a wide range of cancer cell linesCell Death Dis.12(7),698(2021)
Morel, I., Cillard, J., Lescoat, G., et al.Antioxidant and free radical scavenging activities of the iron chelators pyoverdin and hydroxypyrid-4-ones in iron-loaded hepatocyte cultures: Comparison of their mechanism of protection with that of desferrioxamineFree Radic. Biol. Med.13(5),499-508(1992)
Prasanthi, J.R., Schrag, M., Dasari, B., et al.Deferiprone reduces amyloid-β and tau phosphorylation levels but not reactive oxygen species generation in hippocampus of rabbits fed a cholesterol-enriched dietJ. Alzheimers Dis.30(1),167-182(2012)
