Telaprevir
Cat. No.：YN370241
CAS No. ：402957-28-2
| 产品名称: | Telaprevir |
| CAS No.: | 402957-28-2 |
| Chemical Name: | (1S,3aR,6aS)-(2S)-2-cyclohexyl-N-(2-pyrazinylcarbonyl)glycyl-3-methyl-L-valyl-N-[(1S)-1-[2-(cyclopropylamino)-2-oxoacetyl]butyl]octahydro-cyclopenta[c]pyrrole-1-carboxamide |
| Synonyms: | 特拉匹韦; VX-950 |
| 分子量: | 679.85 |
| 分子式: | C₃₆H₅₃N₇O₆ |
| SMILES: | O=C(N([C@@H]1C(N[C@H](C(C(NC2CC2)=O)=O)CCC)=O)C[C@@]3(CCC[C@@]31[H])[H])[C@@H](NC([C@@H](NC(C4=NC=CN=C4)=O)C5CCCCC5)=O)C(C)(C)C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Telaprevir 是一种有效的选择性的可逆HCV NS3-4A protease抑制剂，作用于基因 1型 (H株) NS3 蛋白酶结构域和 NS4A 辅因子肽，Ki为 7 nM。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Perni, R.B., Almquist, S.J., Byrn, R.A., et al.Preclinical profile of VX-950, a potent, selective, and orally bioavailable inhibitor of hepatitis C virus NS3-4A serine proteaseAntimicrob. Agents Chemother.50(3),899-909(2006)
