Narlaprevir
Cat. No.:YN370254
CAS No. :865466-24-6
产品名称: | Narlaprevir |
CAS No.: | 865466-24-6 |
Chemical Name: | (1R,2S,5S)-N-[(1S)-1-[(Cyclopropylamino)oxoacetyl]pentyl]-3-[(2S)-2-[[[[1-[[(1,1-dimethylethyl)sulfonyl]methyl]cyclohexyl]amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]-6,6-dimethyl-, 3-Azabicyclo[3.1.0]hexane-2-carboxamide; Sch 900518 |
Synonyms: | 那拉匹韦; SCH 900518 |
分子量: | 707.96 |
分子式: | C₃₆H₆₁N₅O₇S |
SMILES: | O=S(CC1(NC(N[C@H](C(N2[C@@H]([C@@]3([H])C(C)([C@]3(C2)[H])C)C(N[C@H](C(C(NC4CC4)=O)=O)CCCC)=O)=O)C(C)(C)C)=O)CCCCC1)(C(C)(C)C)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Narlaprevir是口服生物相容性的NS3蛋白酶抑制剂,Ki为6 nM,EC90为40 nM。 |
IC50和靶点: | |
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Solvent & Solubility: |
Wang, H. et al.: Biochem. Cell Biol., 92, 357 (2014)
Li, J. et al.: Int. J. Mol. Sci., 14, 22845 (2013)