Paritaprevir
Cat. No.：YN371040
CAS No. ：1216941-48-8
| 产品名称: | Paritaprevir |
| CAS No.: | 1216941-48-8 |
| Chemical Name: | (2R,6S,12Z,13aS,14aR,16aS)-N-(cyclopropylsulfonyl)-1,2,3,6,7,8,9,10,11,13a,14,15,16,16a-tetradecahydro-6-[[(5-methyl-2-pyrazinyl)carbonyl]amino]-5,16-dioxo-2-(6-phenanthridinyloxy)-cyclopropa[e]pyrrolo[1,2-a][1,4]diazacyclopentadecine-14a(5H)-carboxamide |
| Synonyms: | ABT-450; Veruprevir |
| 分子量: | 765.88 |
| 分子式: | C₄₀H₄₃N₇O₇S |
| SMILES: | O=C([C@]1(NC([C@@]2([H])N3C[C@H](OC4=C(C=CC=C5)C5=C6C(C=CC=C6)=N4)C2)=O)[C@H](/C=C\CCCCC[C@H](NC(C7=NC=C(C)N=C7)=O)C3=O)C1)NS(=O)(C8CC8)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Paritaprevir是一种有效的非结构蛋白 3/4A (NS3/4A) 蛋白酶抑制剂, 对 HCV 1a 和 1b 的EC50值分别为 1 和 0.21 nM。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Pilot-Matias, T., Tripathi, R., Cohen, D., et al.In vitro and in vivo antiviral activity and resistance profile of the hepatitis C virus NS3/4A protease inhibitor ABT-450Antimicrob. Agents Chemother.59(2),988-997(2015)
