Asunaprevir
Cat. No.:YN372204
产品名称: | Asunaprevir |
CAS No.: | 630420-16-5 |
Chemical Name: | (1R,2S)-N-[(1,1-dimethylethoxy)carbonyl]-3-methyl-L-valyl-(4R)-4-[(7-chloro-4-methoxy-1-isoquinolinyl)oxy]-L-prolyl-1-amino-N-(cyclopropylsulfonyl)-2-ethenyl-cyclopropanecarboxamide |
Synonyms: | BMS-650032 |
分子量: | 748.29 |
分子式: | C₃₅H₄₆ClN₅O₉S |
SMILES: | ClC1=CC=C2C(C(O[C@H]3CN(C([C@@H](NC(OC(C)(C)C)=O)C(C)(C)C)=O)[C@H](C(N[C@@]4(C(NS(C5CC5)(=O)=O)=O)[C@H](C=C)C4)=O)C3)=NC=C2OC)=C1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Asunaprevir (BMS-650032) 是一种有效的,具有口服活性的hepatitis C virus (HCV) NS3 protease抑制剂,IC50值为 0.2 nM-3.5 nM。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Zhang, X.Direct anti-HCV agentsActa Pharmaceutica Sinica B6(1),26-31(2015)
Alavian, S.M., and Rezaee-Zavareh, M.S.Daclatasvir-based treatment regimens for hepatitis C virus infection: A systematic review and meta-analysisHepat. Mon.16(9),e41077(2016)