Glecaprevir
Cat. No.：YN372463
CAS No. ：1365970-03-1
| 产品名称: | Glecaprevir |
| CAS No.: | 1365970-03-1 |
| Chemical Name: | (1R,2R)-N-[[[(1R,2R)-2-[[4,4-difluoro-4-(3-hydroxy-2-quinoxalinyl)-2-buten-1-yl]oxy]cyclopentyl]oxy]carbonyl]-3-methyl-L-valyl-(4R)-4-hydroxy-L-prolyl-1-amino-2-(difluoromethyl)-N-[(1-methylcyclopropyl)sulfonyl]-cyclopropanecarboxamide, cyclic (1→2)-ether |
| Synonyms: | ABT-493 |
| 分子量: | 838.87 |
| 分子式: | C₃₈H₄₆F₄N₆O₉S |
| SMILES: | O=C([C@H]1N(C([C@@H](NC(O[C@@]2([H])[C@@]3([H])CCC2)=O)C(C)(C)C)=O)C[C@@](OC4=NC5=CC=CC=C5N=C4C(F)(/C=C/CO3)F)([H])C1)N[C@]6([C@H](C(F)F)C6)C(NS(=O)(C7(CC7)C)=O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Glecaprevir 是一种新型的 HCV NS3/4A 蛋白酶 (HCV NS3/4A protease) 抑制剂，其IC50值在 3.5 和 11.3 nM 之间。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Ng, T.I., Tripathi, R., Reisch, T., et al.In vitro antiviral activity and resistance profile of the next-generation hepatitis C virus NS3/4A protease inhibitor glecaprevirAntimicrob. Agents Chemother.62(1),e01620-01617(2017)
