ITSA-1
Cat. No.：YN290010
CAS No. ：200626-61-5
| 产品名称: | ITSA-1 |
| CAS No.: | 200626-61-5 |
| Chemical Name: | 1H-benzotriazol-1-yl(2,4-dichlorophenyl)-methanone |
| Synonyms: | ITSA1 |
| 分子量: | 292.12 |
| 分子式: | C₁₃H₇Cl₂N₃O |
| SMILES: | O=C(N1N=NC2=CC=CC=C21)C3=CC=C(Cl)C=C3Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | ITSA-1 是HDAC的激活剂，可抵消曲古抑菌素 A (trichostatin A, TSA) 诱导的细胞周期停滞，组蛋白乙酰化和转录水平。 |
| IC50和靶点: | |
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Hoshikawa, Y., Kwon, H.J., Yoshida, M., et al.Trichostatin A induces morphological changes and gelsolin expression by inhibiting histone deacetylase in human carcinoma cell linesExp. Cell Res.214,189-197(1994)
Koeller, K.M., Haggarty, S.J., Perkins, B.D., et al.Chemical genetic modifier screens: Small molecule trichostatin suppressors as probes of intracellular histone and tubulin acetylationChem. Biol.10(5),397-410(2003)
