HDAC8-IN-1
Cat. No.:YN290099
CAS No. :1417997-93-3
产品名称: | HDAC8-IN-1 |
CAS No.: | 1417997-93-3 |
Chemical Name: | (2E)-N-hydroxy-3-(5-methoxy[1,1′:4′,1′′-terphenyl]-2-yl)-2-propenamide |
Synonyms: | HDAC8-IN-1 |
分子量: | 345.39 |
分子式: | C₂₂H₁₉NO₃ |
SMILES: | O=C(NO)/C=C/C1=CC=C(OC)C=C1C2=CC=C(C3=CC=CC=C3)C=C2.[E] |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | HDAC8-IN-1 是一个HDAC8抑制剂,其IC50值为 27.2 nM。 |
IC50和靶点: | [{name:"HDAC8:27.2 nM (IC50)"}] |
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Clinical Trial: | |
Solvent & Solubility: |
Huang, W.-J., Wang, Y.-C., Chao, S.-W., et al.Synthesis and biological evaluation of ortho-aryl N-hydroxycinnamides as potent histone deacetylase (HDAC) 8 isoform-selective inhibitorsChemMedChem7(10),1815-1824(2012)