SR-4370
Cat. No.：YN290102
CAS No. ：1816294-67-3
| 产品名称: | SR-4370 |
| CAS No.: | 1816294-67-3 |
| Chemical Name: | 2',3'-difluoro-[1,1'-biphenyl]-4-carboxylic acid, 2-butylhydrazide |
| Synonyms: | SR 4370 |
| 分子量: | 304.33 |
| 分子式: | C₁₇H₁₈F₂N₂O |
| SMILES: | O=C(C1=CC=C(C2=CC=CC(F)=C2F)C=C1)NNCCCC |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | SR-4370 是一种有效的HDAC抑制剂，对 HDAC1，HDAC2，HDAC3，HDAC8 和 HDAC6 的IC50值分别为 0.13 μM，0.58 μM，0.006 μM，2.3 μM 和 3.4 μM。 |
| IC50和靶点: | [{name:"HDAC3:6 nM (IC50)"},{name: "HDAC1:130 nM (IC50)"},{name: "HDAC2:580 nM (IC50)"},{name: "HDAC8:2300 nM (IC50)"},{name: "HDAC6:3400 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Liao, D., Roush, W.R., and Stowe, R.L.HDAC inhibitor compounds and methods of treatment,(2015)
