ACY-1083
Cat. No.:YN290116
CAS No. :1708113-43-2
产品名称: | ACY-1083 |
CAS No.: | 1708113-43-2 |
Chemical Name: | |
Synonyms: | |
分子量: | 348.35 |
分子式: | C₁₇H₁₈F₂N₄O₂ |
SMILES: | FC(CC1)(F)CCC1(NC2=NC=C(C(NO)=O)C=N2)C3=CC=CC=C3 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | ACY-1083 是一种可渗透脑的选择性HDAC6抑制剂,IC50为 3 nM,ACY-1083 对 HDAC6 的选择性比其他类别的 HDAC 亚型高 260 倍。ACY-1083 可有效逆转化疗引起的周围神经病变。 |
IC50和靶点: | [{name:"HDAC6:3 nM (IC50)"}] |
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Clinical Trial: | |
Solvent & Solubility: |