Quisinostat
Cat. No.：YN290347
CAS No. ：875320-29-9
| 产品名称: | Quisinostat |
| CAS No.: | 875320-29-9 |
| Chemical Name: | N-Hydroxy-2-[4-[[[(1-methyl-1H-indol-3-yl)methyl]amino]methyl]-1-piperidinyl]-5-pyrimidinecarboxamide; JNJ 26481585; Quisinostat |
| Synonyms: | JNJ-26481585 |
| 分子量: | 394.47 |
| 分子式: | C₂₁H₂₆N₆O₂ |
| SMILES: | O=C(C1=CN=C(N2CCC(CNCC3=CN(C)C4=C3C=CC=C4)CC2)N=C1)NO |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Quisinostat (JNJ-26481585) 是一种有口服活性，高效的HDAC抑制剂，对 HDAC1，HDAC2，HDAC4，HDAC10，HDAC11 的IC50值分别为 0.11 nM，0.33 nM，0.64 nM，0.46 nM 和 0.37 nM。 |
| IC50和靶点: | [{name:"HDAC1:0.11 nM (IC50)"},{name: "HDAC2:0.33 nM (IC50)"},{name: "HDAC4:0.64 nM (IC50)"},{name: "HDAC10:0.46 nM (IC50)"},{name: "HDAC11:0.37 nM (IC50)"},{name: "HDAC3:4.86 nM (IC50)"},{name: "HDAC5:3.69 nM (IC50)"},{name: "HDAC8:4.26 nM (IC50)"},{name: "HDAC9:32.1 nM (IC50)"},{name: "HDAC6:76.8 nM (IC50)"},{name: "HDAC7:119 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Kutil, Z., et al.: ACS Omega, 4, 19895 (2019)
