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BRD73954

Cat. No.:YN290440

  • CAS No. :1440209-96-0

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    • 生物活性
    • 参考文献
    • 产品名称: BRD73954
      CAS No.: 1440209-96-0
      Chemical Name: N1-hydroxy-N3-(2-phenylethyl)-1,3-benzenedicarboxamide
      Synonyms:BRD73954;BRD-73954;N-Hydroxy-N′-phenethyl-isophthalamide;N1-Hydroxy-N3-(2-phenylethyl)-1,3-benzenedicarboxamide;N1-Hydroxy-N3-phenethylisophthalamide;BRD 73954;AOB4639;BCP12818;s7726;BDBM50434126;BC600649;AK546304;BRD73954, >=98% (HPLC);B4988;N1-hydroxy-N
      分子量:284.31
      分子式:C₁₆H₁₆N₂O₃
      SMILES:O=C(C1=CC=CC(C(NCCC2=CC=CC=C2)=O)=C1)NO
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: BRD73954 是一种有效的选择性HDAC抑制剂, 作用于HDAC6和HDAC8, IC50分别为36 nM和120 nM。
      IC50和靶点: [{name:"HDAC6:0.036 μM (IC50)"},{name: "HDAC8:0.12 μM (IC50)"},{name: "HDAC2:9 μM (IC50)"}]
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Olson, D.E., Wagner, F.F., Kaya, T., et al.Discovery of the first histone deacetylase 6/8 dual inhibitorsJ. Med. Chem.56(11),4816-4820(2013)

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    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
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