BRD73954
Cat. No.:YN290440
CAS No. :1440209-96-0
产品名称: | BRD73954 |
CAS No.: | 1440209-96-0 |
Chemical Name: | N1-hydroxy-N3-(2-phenylethyl)-1,3-benzenedicarboxamide |
Synonyms: | BRD73954;BRD-73954;N-Hydroxy-N′-phenethyl-isophthalamide;N1-Hydroxy-N3-(2-phenylethyl)-1,3-benzenedicarboxamide;N1-Hydroxy-N3-phenethylisophthalamide;BRD 73954;AOB4639;BCP12818;s7726;BDBM50434126;BC600649;AK546304;BRD73954, >=98% (HPLC);B4988;N1-hydroxy-N |
分子量: | 284.31 |
分子式: | C₁₆H₁₆N₂O₃ |
SMILES: | O=C(C1=CC=CC(C(NCCC2=CC=CC=C2)=O)=C1)NO |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | BRD73954 是一种有效的选择性HDAC抑制剂, 作用于HDAC6和HDAC8, IC50分别为36 nM和120 nM。 |
IC50和靶点: | [{name:"HDAC6:0.036 μM (IC50)"},{name: "HDAC8:0.12 μM (IC50)"},{name: "HDAC2:9 μM (IC50)"}] |
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Solvent & Solubility: |
Olson, D.E., Wagner, F.F., Kaya, T., et al.Discovery of the first histone deacetylase 6/8 dual inhibitorsJ. Med. Chem.56(11),4816-4820(2013)