UF010
Cat. No.：YN290446
CAS No. ：537672-41-6
| 产品名称: | UF010 |
| CAS No.: | 537672-41-6 |
| Chemical Name: | 4-bromo-benzoic acid, 2-butylhydrazide |
| Synonyms: | UF-010; UF 010 |
| 分子量: | 271.15 |
| 分子式: | C₁₁H₁₅BrN₂O |
| SMILES: | O=C(NNCCCC)C1=CC=C(Br)C=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | UF010是一种有效的选择性HADC抑制剂, 作用于HDACs 3, 2, 1 和 8, IC50值分别为 0.06μM, 0.1μM, 0.5μM, 和1.5μM, 比作用于其他HDACs选择性高6倍多。 |
| IC50和靶点: | [{name:"HDAC3:0.06 μM (IC50)"},{name: "HDAC2:0.1 μM (IC50)"},{name: "HDAC1:0.5 μM (IC50)"},{name: "HDAC8:1.5 μM (IC50)"},{name: "HDAC6:9.1 μM (IC50)"},{name: "HDAC10:15.3 μM (IC50)"},{name: "HDAC11:44.5 μM (IC50)"}] |
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| Solvent & Solubility: |
Wang, Y., Stowe, R.L., Pinello, C.E., et al.Identification of histone deacetylase inhibitors with benzoylhydrazide scaffold that selectively inhibit class I histone deacetylasesChem. Biol.22(2),273-284(2015)
