ACY-775
Cat. No.：YN290452
CAS No. ：1375466-18-4
| 产品名称: | ACY-775 |
| CAS No.: | 1375466-18-4 |
| Chemical Name: | 2-[[1-(3-fluorophenyl)cyclohexyl]amino]-N-hydroxy-5-pyrimidinecarboxamide |
| Synonyms: | ACY 775;ACY775 |
| 分子量: | 330.36 |
| 分子式: | C₁₇H₁₉FN₄O₂ |
| SMILES: | O=C(NO)C(C=N1)=CN=C1NC2(CCCCC2)C3=CC=CC(F)=C3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | ACY-775 是一个有效的，选择性强的组蛋白脱乙酰酶 6 (HDAC6) 抑制剂IC50值为 7.5 nM。 |
| IC50和靶点: | [{name:"HDAC6:7.5 nM (IC50)"},{name: "HDAC1:2123 nM (IC50)"},{name: "HDAC2:2570 nM (IC50)"},{name: "HDAC3:11223 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Jochems, J., Boulden, J., Lee, B.G., et al.Antidepressant-like properties of novel HDAC6-selective inhibitors with improved brain bioavailabilityNeuropsychopharmacology39(2),389-400(2014)
