Emtricitabine S-oxide
Cat. No.：YN250012
| 产品名称: | Emtricitabine S-oxide |
| CAS No.: | 152128-77-3 |
| Chemical Name: | 4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone |
| Synonyms: | Emtricitabine sulfoxide; Emtricitabine Degradant-III |
| 分子量: | 263.25 |
| 分子式: | C₈H₁₀FN₃O₄S |
| SMILES: | O=C1N=C(N)C(F)=CN1[C@@H](O[C@H]2CO)CS2=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Emtricitabine S-oxide (Emtricitabine sulfoxide) 是 Emtricitabine 的主要降解产物。Emtricitabine 是一种有效的核苷类逆转录酶抑制剂，可用于研究 HIV 感染。 |
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Mali, A., and More, U.RP-HPLC method for simultaneous estimation of impurities from emtricitabine and tenofovir disoproxil fumarate tabletInt. J. Pharm. Sci. Res.7(4),1662-1669(2016)
Nelson, M., and Schiavone, M.Emtricitabine (FTC) for the treatment of HIV infectionInt. J. Clin. Pract.58(5),504-510(2004)
Darque, A., Valette, G., Rousseau, F., et al.Quantitation of intracellular triphosphate of emtricitabine in peripheral blood mononuclear cells from human immunodeficiency virus-infected patientsAntimicrob. Agents Chemother.43(9),2245-2250(1999)
Seignères, B., Martin, P., Werle, B., et al.Effects of pyrimidine and purine analog combinations in the duck hepatitis B virus infection modelAntimicrob. Agents Chemother.47(6),1842-1852(2003)
Korba, B.E., Schinazi, R.F., Cote, P., et al.Effect of oral administration of emtricitabine on woodchuck hepatitis virus replication in chronically infected woodchucksAntimicrob. Agents Chemother.44(6),1757-1760(2000)
