Delavirdine
Cat. No.：YN250118
| 产品名称: | Delavirdine |
| CAS No.: | 136817-59-9 |
| Chemical Name: | N-[2-[[4-[3-[(1-Methylethyl)amino]-2-pyridinyl]-1-piperazinyl]carbonyl]-1H-indol-5-yl]methanesulfonamide; BHAP-U 90152; U-90152; 1-[3-(Isopropylamino)-2-pyridyl]-4-[(5-methanesulfonamidoindol-2-yl)carbonyl]piperazine; |
| Synonyms: | 地拉韦啶; U 90152; BHAP-U 90152 |
| 分子量: | 456.56 |
| 分子式: | C₂₂H₂₈N₆O₃S |
| SMILES: | O=S(NC1=CC=C(NC(C(N2CCN(C3=C(NC(C)C)C=CC=N3)CC2)=O)=C4)C4=C1)(C)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Delavirdine (U 90152; BHAP-U 90152) 是一种有效的口服活性非核苷逆转录酶抑制剂 (NNRTI)。Delavirdine 选择性地抑制 HIV-1 逆转录酶 (HIV-1 RT) (IC50=0.26 μM)，选择性超过 DNA 聚合酶 α (IC50=440 μM) 和 DNA 聚合酶 δ (IC50>550 μM)。Delavirdine 是HIV-1 病毒复制的抑制剂，可以用于艾滋病的相关研究。 |
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| Solvent & Solubility: |
Dueweke, T.J., et al.: Antimicrob. Ag. Chemother., 37, 1127 (1993), Althaus, I.W., et al.: Biochem. Pharmacol., 47, 2017 (1994)
