Mitoguazone
Cat. No.：YN250135
| 产品名称: | Mitoguazone |
| CAS No.: | 459-86-9 |
| Chemical Name: | |
| Synonyms: | 米托瓜酮; Methylglyoxal-bis(guanylhydrazone); MGBG; Methyl-GAG |
| 分子量: | 184.20 |
| 分子式: | C₅H₁₂N₈ |
| SMILES: | CC(/C=N/NC(N)=N)=N\NC(N)=N |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Mitoguazone (Methylglyoxal-bis(guanylhydrazone)) 是一种具有有效抗肿瘤活性的合成多羰基衍生物。Mitoguazone 是一种可透过血脑屏障的竞争性的 S-腺苷-蛋氨酸脱羧酶 (S-adenosyl-methionine decarboxylase) 抑制剂，可破坏多胺的生物合成。Mitoguazone 诱导细胞凋亡 (apoptosis)，可抑制HIV DNA整合到单核细胞和巨噬细胞中的细胞 DNA 中。Mitoguazone 具可用于急性白血病，霍奇金淋 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
